
Cortisone acetate
CAS No. 50-04-4
Cortisone acetate( Cortisone 21-acetate )
Catalog No. M14679 CAS No. 50-04-4
Cortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
100MG | 51 | In Stock |
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500MG | 87 | In Stock |
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Biological Information
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Product NameCortisone acetate
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NoteResearch use only, not for human use.
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Brief DescriptionCortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester.
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DescriptionCortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester; the C21 acetate ester of cortisone and acts as a prodrug of cortisone in the body.Allergy Approved(In Vitro):Cortisone (2.8-28,000 nM) dose-dependently attenuates the apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs).(In Vivo):Cortisone (2 mg/kg; i.m. on alternate days for 2 months) decreases the BCG (the vaccine strain of tubercle bacillus) lesions and tuberculin reactions in rabbits.
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In VitroCortisone (2.8-28,000 nM) dose-dependently attenuates the apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs).
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In VivoCortisone (2 mg/kg; i.m. on alternate days for 2 months) decreases the BCG (the vaccine strain of tubercle bacillus) lesions and tuberculin reactions in rabbits. Animal Model:Male New Zealand white rabbits (2.1-2.4 kg) were injected with BCG at six days after the first administrtion Dosage:2 mg/kg Administration:Intramuscular injection on alternate days for 2 months Result:Reduced the BCG lesions and tuberculin reactions.Reduced the number of infiltrating mononuclear cells (MN), the amount of caseous necrosis and ulceration, and the percent of NM that were beta-galactosidase-positive.
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SynonymsCortisone 21-acetate
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PathwayEndocrinology/Hormones
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TargetGR
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RecptorGlucocorticoidReceptor
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Research AreaInflammation/Immunology
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IndicationAllergy
Chemical Information
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CAS Number50-04-4
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Formula Weight402.4807
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Molecular FormulaC23H30O6
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Purity>98% (HPLC)
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SolubilityDMSO: 6.8 mg/mL (Need ultrasonic and warming)
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SMILESCC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
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Chemical NamePregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy- (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog



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